p-Aminophenol may be obtained by the amide hydrolysis of paracetamol. p-Aminophenol prepared this way, and related to the commercially available Metol, has been used as a developer in photography by hobbyists. This reaction is also used to determine paracetamol in urine samples: After hydrolysis with hydrochloric acid, p-aminophenol reacts in ammonia solution with a phenol derivate e.g. salicylic acid to form an indophenol dye under oxidization by air.
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